Fig. 7: Anatomical patterns of neurochemical clusters.

Statistical maps of the comparison between the lesion topography (upper rows) and structural disconnectome (lower rows) maps of each neurochemical cluster with the remaining clusters, in the validation set. The orange-red and the cyan-blue colourmaps represent the significantly higher or lower probability of lesion/disconnection, respectively (nonparametric two-sample unpaired permutation test, based on 5000 permutations). P-values were family-wise error rate (FWE) corrected for multiple comparisons. Only the clusters with statistically significant associations are shown. Images are presented according to the radiological convention (in axial slices, the left hemisphere corresponds to the right side of the picture). The sample sizes for clusters 1, 2, 4 and 5 are, respectively, 32, 18, 39, and 10.