Fig. 2: Serum concentrations of vitamin D metabolites by allocation and timepoint.

A total 25(OH)D concentrations; (B) total 24 R,25(OH)2D concentrations; (C) 25(OH)D-to-24R,25(OH)2D ratios. P values are from generalised mixed models, testing for effect of allocation to vitamin D vs placebo with adjustment for baseline value and study site. Statistical tests were 2-sided, with no adjustment for multiple comparisons. Source data are provided as a Source Data file.