Fig. 1: Rehabilitative training recovers motor performance after stroke. | Nature Communications

Fig. 1: Rehabilitative training recovers motor performance after stroke.

From: Parvalbumin interneurons regulate rehabilitation-induced functional recovery after stroke and identify a rehabilitation drug

Fig. 1

a Rehabilitation box used in the study. Mice stably engage in reach-to-grasp training for 3 weeks, 5 days a week during recovery. n = 12. The error bars are smaller than the symbols. b Timeline of rehabilitation and behavioral testing. The blue triangles indicate behavioral tests. Pretraining for behavior tests and rehabilitation periods are indicated as blue and red rectangles. c, d Skilled reaching test (c): success rate (time by group, F (6, 64) = 10.35, P < 0.0001) and grid walk test (d): foot fault rate (time by group, F (6, 64) = 26.49, P < 0.0001). Two-way repeated measure ANOVA with Sidak’s multiple comparison test. **P < 0.01, ***P < 0.001. e, f Functional improvement in the recovery period in the skilled reaching test (e) and the grid walk test (f). Two-tailed paired t-test. (a–f) n = 8 (Sham), 8 (Sham + Rehab), 10 (Stroke) or 9 (Stroke + Rehab). (b) Created in BioRender127.

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