Fig. 6: Binding modes of cyclic peptides. | Nature Communications

Fig. 6: Binding modes of cyclic peptides.

From: Structure of a lasso peptide bound ETB receptor provides insights into the mechanism of GPCR inverse agonism

Fig. 6

a Cavity for RES-701-3. The ETB receptor is shown as a molecular surface. b, c Cavities for MccJ25 in bacterial RNA polymerase (PBD 6N60) (b) and the siderophore receptor FhuA (PBD 4CU4) (c). d Crystal structures of the P. furiosus MATE transporter bound to the thioether-macrocyclic peptides MaD3S (PBD 3VVS) and MaL6 (PBD 3WBN).

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