Fig. 3: BiFC analysis of StlP, CslA, and GlxA interactions in Streptomyces.

Detection of interactions between the stomatin-like protein (StlP) and the cellulose synthase-like protein (CslA) (A), StlP and the galactose oxidase-like protein (GlxA) (B), and CslA and GlxA (C) using bimolecular fluorescence complementation (BiFC). The wild-type Streptomyces coelicolor M145 strain was transformed with plasmids expressing the indicated protein fusion pairs. Control experiments with M145 strain expressing individual protein fusion are presented in Supplementary Fig. 9. White arrows indicate the appearance of enhanced-green fluorescent protein (eGFP) fluorescence at hyphal tips demonstrating interactions between respective protein pairs. Bars represent 10 μm for all images.