Fig. 5: Phylogenetic analysis of the distribution of StlP proteins in Proteobacteria.

Maximum-likelihood was used to construct the phylogenetic trees. Position-Specific Iterative (PSI)-BLAST and TransMembrane Hidden Markov Model (TMHMM) prediction were used to identify StlP homologs in the dataset of 15,405 reference sequence database (RefSeq) representative bacteria and archaea (left panel). The right panel indicates the distribution of StlP homologs in the genus of actinobacteria. The inner strips indicate different phyla (left panel) or genera (right panel), represented by different colors, while the outside black strip indicates StlP homologs. The green and pink arrowheads represent Streptomyces coelicolor A3(2) and Kitasatospora viridifaciens DSM40239, respectively.