Fig. 8: Epigenetic subgroups in the SCAN-B TNBC validation cohort.
From: The DNA methylation landscape of primary triple-negative breast cancer
a Circular heatmap showing 136 samples classified into five DNA methylation subgroups as columns and the following characteristics as rows: PAM50 and TNBCtype subtypes, different expression metagenes (basal, steroid response, immune response, stroma), patient age at diagnosis, FASN expression, and gene network3 (metabolism-associated) expression. b PD-L1 and PD-L2 expression against beta values of the correlated cg19724470 and cg07211259 CpGs respectively located close to their TSSs, divided by Basal subgroups. Boxplot elements correspond to: (i) center line = median, (ii) box limits = upper and lower quartiles, (iii) whiskers = 1.5x interquartile range. Source data are provided as a Source Data file.
