Table 1 Characteristics of the study cohort categorized by perioperative organ injury

From: Impact of perioperative organ injury on morbidity and mortality in 28 million surgical patients

Characteristic

All patients (N = 28,350,953)

Patients with POI— (N = 1,245,898)

Patients without POI (N = 27,105,055)

Median age (IQR)—yrs

59 [39–74]

76 [66–82]

58 [38–73]

Female sex—no. (%)

15,390,796 (54.3)

516,057 (41.4)

14,874,739 (54.9)

Hospital admission type—no. (%)

Ā Ā Ā 

ā€ƒReferral from physician

19,309,039 (68.1)

384,096 (30.8)

18,924,943 (69.8)

ā€ƒEmergency

8,287,300 (29.2)

681,935 (54.7)

7,605,365 (28.1)

ā€ƒTransfer from another hospital

733,057 (2.6)

179,105 (14.4)

553,952 (2.0)

ā€ƒTransfer from rehabilitation

2188 (<0.1)

383 (<0.1)

1805 (<0.1)

ā€ƒBirth

19,369 (<0.1)

379 (<0.1)

18,990 (<0.1)

Median Charlson comorbidity index (IQR)—pts

0 [0–2]

3 [1–5]

0 [0–1]

Charlson Comorbidity Index Items—no. (%)

Diabetes mellitus

3,843,335 (13.6)

392,551 (31.5)

3,450,784 (12.7)

ā€ƒUncomplicated

2,952,801 (10.4)

258,435 (20.7)

2,694,366 (9.9)

ā€ƒWith end-organ damage

890,534 (3.1)

134,116 (10.8)

756,418 (2.8)

Cancer

3,156,980 (11.1)

221,567 (17.8)

2,935,413 (10.8)

ā€ƒNon-metastatic

2,246,180 (7.9)

133,818 (10.7)

2,112,362 (7.8)

ā€ƒMetastatic

910,800 (3.2)

87,749 (7.0)

823,051 (3.0)

Renal disease

2,336,360 (8.2)

406,537 (32.6)

1,929,823 (7.1)

Congestive heart failure

1,910,719 (6.7)

427,143 (34.3)

1,483,576 (5.5)

Chronic obstructive pulmonary disease

1,750,439 (6.2)

169,875 (13.6)

1,580,564 (5.8)

Peripheral vascular disease

1,670,506 (5.9)

227,379 (18.3)

1,443,127 (5.3)

Cerebrovascular disease

812,635 (2.9)

177,533 (14.2)

635,102 (2.3)

History of myocardial infarction

599,614 (2.1)

67,993 (5.5)

527,621 (1.9)

Dementia

634,339 (2.2)

126,623 (10.2)

507,716 (1.9)

Hemiplegia or paraplegia

574,671 (2.0)

160,401 (12.9)

414,270 (1.5)

Liver disease

546,908 (1.9)

79,929 (6.4)

466,979 (1.7)

ā€ƒMild

418,008 (1.5)

52,203 (4.2)

365,805 (1.3)

ā€ƒModerate to severe

128,900 (0.5)

27,726 (2.2)

101,174 (0.4)

Rheumatoid disease

292,112 (1.0)

21,018 (1.7)

271,094 (1.0)

Peptic ulcer disease

230,826 (0.8)

53,472 (4.3)

177,354 (0.7)

AIDS

9179 (<0.1)

934 (<0.1)

8236 (<0.1)

High-risk surgeries—no. (%)*

9,546,235 (33.7)

848,557 (68.1)

8,697,678 (32.1)

ā€ƒAbdominal surgery

6,596,343 (23.3)

407,507 (33.7)

6,188,836 (22.8)

ā€ƒThoracic surgery†

1,530,479 (5.4)

184,536 (14.8)

1,345,943 (5.0)

ā€ƒCardiac surgery

1,101,545 (3.9)

207,308 (16.6)

894,237 (3.3)

ā€ƒIntracranial surgery

304,022 (1.1)

46,128 (3.7)

257,894 (1.0)

ā€ƒTransplantation surgery

13,846 (<0.1)

3078 (0.2)

10,768 (<0.1)

  1. *High-risk surgeries included abdominal surgery, thoracic surgery, cardiac surgery, intracranial surgery, and transplantation surgery.
  2. †Thoracic surgery does not include cardiac surgery.
  3. —Any kind of perioperative organ injury.
  4. POI perioperative organ injury, AIDS autoimmune deficiency syndrome.