Fig. 5: Results of the reductive-coupling of nitro compounds with alcohols.
Reaction conditions: nitro compounds (0.5 mmol), MgO/NC-500 (30.0 mg), aromatic alcohols (2.5 mmol), hexane (10 mL), N2 (10 bar), and 200 °C; aliphatic alcohols were also used as the reaction solvents when they were used; 10 equiv. of 1, 2-diols were used for the synthesis of quinoxaline. A Synthesis of imines; B Synthesis of benzimidazole; C Synthesis of quinoxaline; D Limitations of nitro compounds. Yields were determined by GC using ethylbenzene as the internal standard, and the data in brackets are the isolated yields. Note: Black balls represent amino or hydroxyl groups on substrate molecules; red and dark red represent alkyl or aryl groups on alcohol molecules.
