Fig. 5: Differential AS between neuron types.
From: Alternative splicing across the C. elegans nervous system
A Euler plot of the number of genes presenting differential alternative splicing (DAS) in this analysis, and from a literature review (Supp. Data 3). Source data are provided as a Source Data file. B Proportion of genes DAS within families of neuronally significant genes56. The number of genes in the family is indicated inside each bar. Hypergeometric test: * Significantly enriched, # significantly depleted. One-sided hypergeometric test and Benjamini-Hochberg correction for multiple comparisons. Exact p-values reported in Source Data file. C Proportion of DAS genes per neuron pair, among genes co-expressed in the neurons of this pair. D Number of DAS genes plotted against number of differentially expressed genes for each neuron pair. The line corresponds to a linear fit, the shaded area to the 95% confidence interval. E Estimate of the number of genes in which DAS can be detected relative to the number of neuron types sequenced. Each subsampling was repeated 10 times; the box plots are centered on the median and between the first and third quartiles, the whiskers extend to the furthest value no further than 1.5 times the interquartile range. Source data are provided as a Source Data file.
