Table 1 Sequence features presenting a statistically significant difference between DAS events and non-DAS events. Two-sided Wilcoxon tests with Benjamini-Hochberg correction for multiple comparisons
From: Alternative splicing across the C. elegans nervous system
Event type | Feature | Median when DAS | Median when not DAS | p-value (adjusted) | |
|---|---|---|---|---|---|
Alt. first exon | Proximal exon length | 174 bp | 129 bp | 0.0021 | ** |
Cassette exon | Exon length | 83 bp | 110 bp | 0.0030 | ** |
Alt. first exon | Distal intron length | 4464 bp | 3754 bp | 0.0220 | * |
Alt. 5’ splice site | Intron length | 238 bp | 138 bp | 0.0253 | * |
Alt. first exon | Proximal intron conservation | 0.4040 | 0.4728 | 0.0260 | * |
Alt. first exon | Distal exon length | 129 bp | 105 bp | 0.0262 | * |
Alt. 5’ splice site | Overhang conservation | 0.9927 | 0.9521 | 0.0663 | # |
Alt. last exon | Distal exon conservation | 0.6122 | 0.6641 | 0.0663 | # |
Alt. last exon | Distal intron length | 2482 bp | 1231 bp | 0.0663 | # |
Mutually exclusive exons | First upstream intron conservation | 0.5005 | 0.3695 | 0.0663 | # |
Mutually exclusive exons | Second exon length | 113 bp | 137 bp | 0.0663 | # |
Cassette exon | Exon conservation | 0.9826 | 0.9772 | 0.0663 | # |
Cassette exon | Upstream intron GC content | 31.06% | 31.72% | 0.0663 | # |
