Table 1 Summary of the datasets used in this study
MGH COVID proteomics | KORA metabolomics | KORA multi-omics | Extended KORA metabolomics | |
|---|---|---|---|---|
Omics type | proteomics | metabolomics | metabolomics; proteomics | metabolomics |
View | ||||
\({{\rm{v}}}1\) | panel: Explore 384 cardiometabolic | biochemical class*: GPL | omics: metabolomics | biochemical class*: GPL |
\({{\rm{v}}}2\) | panel: Explore 384 inflammation | biochemical class*: AC, SL, AA, MS | omics: proteomics | biochemical class*: AC, SL, AA, MS |
Variable number | Explore 384 cardiometabolic: 322, Explore 384 inflammation: 295 | GPL: 70, AC: 15, SL: 11, AA: 9, MS: 1 | metabolites: 104, proteins: 66 | GPL: 69, AC: 14, SL: 11, AA: 9, MS: 1 |
Timepoint | ||||
\({{\rm{t}}}1\) | D0 | F4 | S4 | S4 |
\({{\rm{t}}}2\) | D3 | FF4 | F4 | F4 |
\({{\rm{t}}}3\) | FF4 | |||
Time span | 3 days | 7 years | 7 years | 14 years in total |
Sample number | ||||
Total (100%) | 218 | 2085 | 1062 | 614 |
Training (64%) | 140 | 1335 | 680 | 393 |
Validation (16%) | 35 | 333 | 170 | 98 |
Test (20%) | 43 | 417 | 212 | 123 |
Masked data for completion | inflammation proteins from D3 | non-GPL metabolites from FF4 | proteins from F4 | completion 1: Non-GPL metabolites from S4;completion 2: GPL metabolites from FF4 |
