Fig. 6: Blood-brain barrier (BBB) permeability-surface area (PS) product of 18F-fluorodeoxyglucose (FDG) and blood glucose level. | Nature Communications

Fig. 6: Blood-brain barrier (BBB) permeability-surface area (PS) product of 18F-fluorodeoxyglucose (FDG) and blood glucose level.

From: Quantitative PET imaging and modeling of molecular blood-brain barrier permeability

Fig. 6

a FDG BBB PS parametric images averaged across blood glucose ranges showed that FDG PS decreased with higher blood glucose levels, with notable decreases at hyperglycemia (> 125 mg/dL; N = 5). b Cohort-level Michaelis-Menten transporter kinetics across 64 analyzed subjects with total-body dynamic FDG positron emission tomography. PS is in units of ml/min/cm3.

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