Fig. 7: Localisation co-dependency among DC-dependent proteins identifies an additional DC component.
From: Proteins with proximal-distal asymmetries in axoneme localisation control flagellum beat frequency
A Change in pDC localisation following deletion of proteins with a localisation dependent on pDC. In the first column, micrographs of L. mexicana cell line expressing proteins tagged with mNG at the C terminus. In columns 2 to 4, micrographs after deletion of FLAM6, LmxM.29.0240 or LmxM.31.2530. B Change in dDC localisation following deletion of proteins with a localisation dependent on dDC. Micrographs of L. mexicana cell line expressing dDC2 protein tagged with mNG at the C terminus, before and after deletion of both alleles of LC4-like and LmxM.30.0090. C Combinatorial tagging and deletion of pDC1 and proteins analysed in A. In the first column, micrographs of L. mexicana cell line expressing proteins tagged with mNG at the C terminus. In columns 2 to 4, micrographs after deletion of FLAM6, LmxM.29.0240 or LmxM.31.2530. Cell lines where the protein fails to localise to the axoneme are outlined in orange, and cell lines where the localisation is axonemal but changed are outlined in blue.
