Fig. 2: Risk factors for all-cause and cause-specific mortality after subsequent breast cancer in childhood cancer survivors. | Nature Communications

Fig. 2: Risk factors for all-cause and cause-specific mortality after subsequent breast cancer in childhood cancer survivors.

From: Treatment, toxicity, and mortality after subsequent breast cancer in female survivors of childhood cancer

Fig. 2

BC breast cancer, RT radiation therapy, CV cardiovascular, SMN subsequent malignant neoplasm. HRs and corresponding 95% confidence intervals (CIs, shown as error bars) from multivariable Cox proportional hazards regression models evaluating associations between primary and breast cancer treatments and the mortality hazard rate using age as the time scale and adjusting for covariates included above are shown, as well as breast cancer diagnosis year and histology (invasive versus non-invasive) or stage (III/IV versus I/II, invasive carcinomas only) (n = 314 overall). HRs and 95% CIs are annotated for statistically significant variables (two-sided P < 0.05). Primary cancer chest RT dose is provided per 10 Gray and primary anthracycline dose is provided per 100 mg/m2.

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