Fig. 7: Optogenetic modulation of LGN neuronal spike timing.

a Rasters and PSTHs for a representative parvocellular Off LGN neuron showing responses to the flashing black spot without (top, black) and with (bottom, blue) synchronized LED stimulation. Time = 0 is spot onset. b Rasters and PSTHs for a representative magnocellular On LGN neuron, conventions as in (a). c Spike timing reliability without (gray) and with (blue) LED stimulation for On (open) and Off (filled) LGN neurons. Neurons of unknown On/Off type indicated in light gray (see legend top right). Open and filled diamonds (interior) illustrate averages for On and Off LGN neurons per LED condition; error bars are SEMs, blue asterisks indicate significant differences (see Table 3 for statistics). d Spike timing jitter without (left) and with (right) LED stimulation; conventions as in (c). e The probability of single-spike words without (left) and with (right) LED stimulation; conventions as in (c, d). Source data are provided in Source Data file.