Fig. 2: Radio-pathological and Biological Peculiarities of MOFS Subtypes. | Nature Communications

Fig. 2: Radio-pathological and Biological Peculiarities of MOFS Subtypes.

From: Multimodal fusion of radio-pathology and proteogenomics identify integrated glioma subtypes with prognostic and therapeutic opportunities

Fig. 2

A Pathological (H&E stain) and radiological (CE-T1WI MRI) images of MOFS1, MOFS2, and MOFS3. MOFS1: Regular cell morphology with weak atypia; no or limited significant enhancement. MOFS2: Varied cell size and significant atypia; mass-like enhancement. MOFS3: Significant atypia and immune cell infiltration; ring-like enhancement with necrotic core (n = 116). Scale bars in the subfigures of pathological images, 50 μm. The size of the pathological image patch is 1024 × 1024 pixels, with each pixel representing 0.50 microns. B Multi-omics characterizes of MOFS subtypes (n = 116). C Enriched pathway analysis using the Metascape tool, highlighting distinct biological processes and signaling pathways for each MOFS subtype.

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