Fig. 3: Pairwise interaction strengths and relative concentrations determine condensate architectures and interfacial features.
From: Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates
a The interaction strengths between polymer beads used in the simulations. The interaction between beads of polymers A and B was varied from –4 to –4.5. b Molecules A, B, C represent poly-rA, PEG and poly-rC respectively. c Representative snapshots from LaSSI simulations showing distinct condensate architectures obtained by varying the interaction strength between beads of polymers A and B, |εB-A | = –4, –4.25, –4.5. For this same titration, we show d the radial density profiles and e the average cos2θ values, which indicate the average orientation of molecules with respect to the center of the condensate (Supplementary Methods). If a given datapoint had an error greater than 0.1, then that datapoint was omitted. In d and e, error bars indicate the standard errors about the mean across three replicates. Source data are provided—see “Data availability” statement.
