Fig. 7: Basal bias neurons in primary visual cortex (V1).
From: An unsupervised map of excitatory neuron dendritic morphology in the mouse visual cortex
A Side view of the cortical volume. Each point represents the soma location of one neuron and is colored by its respective basal bias (dark = negative basal bias: center of mass of basal dendrites is above the soma; bright = positive basal bias: center of mass of basal dendrites is below soma). B Example neuronal morphologies of basal bias neurons (top) and top view of the volume (as in Fig. 6B) showing horizontal density distribution of L4 cells whose dendrites avoid reaching into L5 and who are mostly located in V1 (bottom). C Functional digital twins can predict the functional response of the neurons to input stimuli such as natural movies. The input-output function of each neuron is described by a functional bar code fi26. Schematic adapted from “Functional connectomics reveals general wiring rule in mouse visual cortex'', Ding et al. bioRxiv 2023.03.13.531369; https://doi.org/10.1101/2023.03.13.531369 under a CC BY license: https://creativecommons.org/licenses/by/4.0/. D Predictions of basal bias metric from functional bar code fi using linear regression. Source data are provided as a Source Data file.
