Fig. 2: Quantile-Quantile plot and Manhattan plot of the South African JCS BC association results.

A Quantile-Quantile (QQ) plot, λ = 1.014. B Manhattan plot with genome-wide significant hits (p < 5 × 10−08) highlighted on chromosomes 15 and 17. Red line indicates genome-wide significance (p < 5 × 10−08), blue line indicates suggestive significance (p < 5 × 10−06). JCS Johannesburg Cancer Study, BC breast cancer, λ Lambda genomic control.