Table 2 Top SNPs associated with African breast cancer from chromosome 15 and 17

From: Genome-wide association study identifies common variants associated with breast cancer in South African Black women

rsID

Chr

Position (hg19)

Gene

Alleles (effect/non-effect)

EAF (cases)

EAF (controls)

OR (95% CI)

p value

Impute2 Score

rs7181788a

15

55015367

UNC13C, RAB27A

T/G

0.252

0.19

1.41 (1.33–1.47)

1.01 × 10−08

1.00

rs899342

17

20924620

USP22

T/C

0.142

0.193

0.68 (0.67– 0.70)

4.62 × 10−08

0.98

  1. SNP is considered genome-wide significant if p-value <5 × 10−08.
  2. EAF effect allele frequency, OR odds ratio, 95% CI 95% confidence interval SNP is considered genome-wide significant if p-value < 5×10−08.
  3. aGenotyped SNP OR and 95% CI calculated in reference to effect allele.
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