Fig. 3: The scope of the light-mediated decarboxylative dearomative difunctionalization. | Nature Communications

Fig. 3: The scope of the light-mediated decarboxylative dearomative difunctionalization.

From: Visible light-mediated dearomative spirocyclization/imination of nonactivated arenes through energy transfer catalysis

Fig. 3

Reaction conditions: oxime 1 (0.3 mmol, 1.5 equiv.), acrylamide 2 (0.2 mmol, 1.0 equiv.), [Ir(dF(CF3)ppy)2(dtbbpy)](PF6) (0.5 mol%), EtOAc (3 mL), N2, blue LEDs (440 nm, 10 W), 2 h, fan cooling (35–40 °C). Diastereomeric ratios (dr) were determined by 1H NMR of the crude reaction mixtures. a4 h reaction time.

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