Fig. 7: A working model of Ym1-mediated wheat yellow mosaic virus (WYMV) resistance.
From: A wheat CC-NBS-LRR protein Ym1 confers WYMV resistance by recognizing viral coat protein
A Ym1 confers WYMV resistance by blocking virus invasion other than Polymyxa graminis (Pg) fungal colonization in the roots. In the left, resistant wheat plant carrying Ym1 and its transverse root; In the right, susceptible plant without Ym1 and its transverse root. In the transverse root model from outer to inner are the epidermis, cortex, endodermis, pericycle and stele cells. The purple elements indicate the colonized Pg; the red curve lines indicate the infected virus. B Diagram showing the Ym1-coat protein (CP) recognition system in wheat resistance against WYMV. Ym1 is root specifically expressed and upregulated upon viral infection. Without viral infection, Ym1 is present as auto-inhibited status. When the virus vectored by Pg infects wheat root cells, auto-inhibited Ym1 is activated by recognizing and interacting with WYMV CP. The activated Ym1 triggers hypersensitive response (HR) or extreme resistance (ER) to inhibit viral replication or movement, results in ultimate outcome to block the virus invasion into root stele.
