Fig. 2: Structure of the AMOP domain from ISM1.
From: Crystal structure of Isthmin-1 and reassessment of its functional role in pre-adipocyte signaling
a Crystal structure of ISM1’s AMOP domain has three helical regions and a central strand core (green). The separate helix regions include the N-terminal helices (blue), the “thumb” (orange), and the C-terminal helix (red). The central stranded (green) projects four fingers. b Schematic of a hand holding chopsticks resembling features of the AMOP fold. c The central stranded core of the AMOP domain (orientation from perspective shown in a). d Three-dimensional alignment between the AMOP domain core and a streptavidin monomer (pink, PDB id: 1STP).
