Fig. 3: Streptavidin-biotin interactions drive bead partitioning into condensates.
From: Controlled and orthogonal partitioning of large particles into biomolecular condensates
a Schematic model of PS-PEG-biotin partitioning into SA-RGG condensates. Streptavidin (SA, which tetramerizes) binds biotin, resulting in bead recruitment into condensates. Created in BioRender. Kelley, F. (2025) https://BioRender.com/o27h472. b Increasing biotin surface density on particles leads to increased partitioning of beads into SA-RGG. (Right) Partition fractions were quantified for each bead. c When biotin surface density is held constant, smaller beads display higher partitioning. (Right) Partition fractions were quantified for each bead. Scale bars, 10 μm. Error bars represent SEM with n = 10 from 2 independent experiments. Source data are provided as a Source Data file.
