Fig. 2: Functional CD8+ T-cell responses measured by ICS. | Nature Communications

Fig. 2: Functional CD8+ T-cell responses measured by ICS.

From: Inflammatory conditions shape phenotypic and functional characteristics of lung-resident memory T cells in mice

Fig. 2

Lymphocytes from rAd-immunized or H1N1-infected mice were isolated, and ICS was used to identify influenza-reactive T cells. HA- and NP-specific cytokine secretion was measured to determine functional CD8+ subpopulations, which are shown for day 35 as frequencies of the circulating (iv+) or tissue-resident (iv-) CD8+ T-cell compartment. Each data point represents an individual mouse, and the bars represent the mean of the group (n = 6 mice per group). Statistical significances were analyzed by a two-tailed Mann-Whitney test (*, p < 0.05; **, p < 0.01).

Back to article page