Fig. 3: Performance characterization of the FIRE system. | Nature Communications

Fig. 3: Performance characterization of the FIRE system.

From: Photon-counting Raman spectroscopy at a MHz spectral rate for biochemical imaging of an entire organism

Fig. 3

a Dark count versus photon count of the measured Raman spectrum of DMSO. b Statistical analysis of dark noise and crosstalk. CTC, crosstalk count. c, Electrical profiles of 1 and 6 photons indicated in a with an FWHM of 4 ns. d Recorded Raman spectrum of pure DMSO within 100 ms. e, Raw data of 19 continuously recorded Raman spectra of DMSO within 19 µs, truncated from (a). f Verification of the shot-noise-limited sensitivity. Error bars: SD (n = 2500 measurements). g Comparison of the sensitivity between FIRE and a Horiba HR800. The O–H background from water was removed for both spectra.

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