Fig. 7: Apt-PRCs promoted dephosphorylation of diverse membrane receptors.

a Schematic illustration of Apt-PRCs ZAJ4a-SL1 action mechanism. b Dephosphorylation effects of Apt-PRCs ZAJ4a-SL1 determined by western blot in Lovo cells. c Quantitative acellular area of wound healing assay (n = 5 independent experiments). d Western blot analysis of Met expression levels in parental PC9 cells and PC9/GR cells. e Western blot analysis of pMet, pAkt and pErk expression levels in PC9/GR cells with different treatments. f The tumor growth curve (n = 5 mice). g The tumor growth inhibition ratio (n = 5 mice). h Tumor weight variation (n = 5 mice). i Representative images of H&E staining and immunohistochemical staining of Ki-67, pMet and pErk of tumors isolated from mice after different treatments. Scale bar: 200 μm. Data are shown as means ± SD, and p-values are determined by two-way ANOVA with Tukey’s multiple comparisons test in (c) and one-way ANOVA with Tukey’s multiple comparisons test in (f–h). The exact p-values are shown in the figure. Uncropped blots of (b–e) were provided in Source Data. Source data are provided as a Source Data file.