Fig. 7: Role of NR2F2 in testicular morphogenesis.

A Schematic representation of the different Nr2f2-positive cell populations identified with our single-nucleus multiomic analysis. B Schematic representation of how NR2F2 controls the identity of the interstitial cells while repressing Fetal Leydig cell differentiation. C Summary figure of the DSD phenotypes in Nr2f2 conditional knockout testis. Created in BioRender, Yao, H. (2025) https://BioRender.com/zg96fxw.