Fig. 2: FOXM1 blocks infiltration of immune cells. | Nature Communications

Fig. 2: FOXM1 blocks infiltration of immune cells.

From: Epigenetic silencing of DNA sensing pathway by FOXM1 blocks stress ligand-dependent antitumor immunity and immune memory

Fig. 2

a–d Representative results from flow cytometry analyses of infiltrated immune cells in tumors from scrambled control (Ctrl; n = 3) and Foxm1 knockout (Foxm1 KO; n = 3) groups. Data are presented as mean values +/- SEM. Representative gates for each group are shown directly below the graphs. e Left: Representative results from flow cytometry analyses of infiltrated myeloid/antigen presenting cell populations in scrambled control (Ctrl; n = 4) and Foxm1 KO (n = 4) tumors. Data are presented as mean values +/− SEM. % Total on the y axis represents % of total living single cells. Right: Representative gates for each myeloid population of cells. p-values for panels (a–d) were calculated using two-sided Welch’s t tests, while p- values for panel (e) was calculated using multiple t test with Benjamini, Krieger, and Yekutieli correction. Control and Foxm1 knockout groups in all bar graphs are represented by dark blue circles or red squares, respectively. Source data are provided as a Source Data file.

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