Table 1 Demographic characteristics for study participants used for transcriptomic analyses comparing severe malaria subtypes to uncomplicated controls without a history of cerebral malaria

From: A shared inflammatory signature across severe malaria syndromes manifested by transcriptomic, proteomic and metabolomic analyses

 

Cerebral malaria

Severe malarial anemia

Concurrent CM and SMA

 

Cases

Controls

p-value

Cases

Controls

p-value

Cases

Controls

p-value

n

12

12

 

8

8

 

8

8

 

Female

5

5

 

6

6

 

2

2

 

Age* (yrs)

2.63 (1.33)

2.78 (1.24)

0.39

2.50 (0.76)

2.75 (0.71)

0.17

3.25 (1.39)

3.25 (1.28)

1

Parasitemia* (parasite/μL)

126,603 (145,769)

33408 (48,930)

0.02

48010 (59,282)

37237 (39,252)

0.69

64,125 (95,799)

9928 (11,418)

0.15

BCS

5

0

12

 

4

8

 

0

8

 

4

0

0

 

1

0

 

0

0

 

3

0

0

 

3

0

 

0

0

 

2

9

0

 

0

0

 

4

0

 

1

3

0

 

0

0

 

4

0

 

Hgb* (g/dL)

7.68 (1.69)

8.87 (1.72)

0.12

2.87 (0.55)

8.41 (1.83)

1.05E-04

3.30 (0.91)

8.11 (2.43)

2.15E-03

  1. *denotes mean (standard deviation). Statistical significance was assessed using a two-tailed t-test.
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