Fig. 3: De novo pan-myeloid subgroups.

a, b Patient samples across myeloid malignancies are visualised in a 2D multidimensional scaling projection based on how well they fit to each cluster-specific network. Each dot represents a patient and is coloured by cancer type (a) or cluster membership (b). Solid-line-encircled shapes depict contours that collectively encompass 50% of the corresponding cluster. Enlarged versions can be found in Supplementary Fig. S2. c Distribution of the patient samples across the clusters. d Kaplan-Meier survival curves illustrate the survival probabilities associated with each cluster. e Barplot displaying the frequency of mutations and cytogenetic alterations across the nine clusters. AML acute myeloid leukemia, CMML chronic myelomonocytic leukemia, MDS myelodysplastic syndromes, MPN myeloproliferative neoplasms. Source data are provided as a Source Data file.