Fig. 2: Comparison of percent of dosed days with large deviations (> 2 ng/ml) from target range during the post-transplant hospitalization between standard-of-care (SOC, n = 29) and Phenotypic Personalized Medicine (PPM, n = 27) dosing groups. | Nature Communications

Fig. 2: Comparison of percent of dosed days with large deviations (> 2 ng/ml) from target range during the post-transplant hospitalization between standard-of-care (SOC, n = 29) and Phenotypic Personalized Medicine (PPM, n = 27) dosing groups.

From: Tacrolimus dosing in liver transplant recipients using phenotypic personalized medicine: A phase 2 randomized clinical trial

Fig. 2

PPM dosing resulted in a lower percent post-transplant days with large deviations from the target range compared to SOC dosing (P = 0.029). Data are presented as a box-and-whiskers plot, where the center line represents the median, the bounds of the box indicate the interquartile range (IQR, 25th to 75th percentile), and the whiskers extend to the minimum and maximum values within 1.5 times the IQR. A two-tailed Wilcoxon Rank Sum test was used to compare the groups.

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