Fig. 2: SNP heritability estimates for DNM counts. | Nature Communications

Fig. 2: SNP heritability estimates for DNM counts.

From: The impact of ancestral, genetic, and environmental influences on germline de novo mutation rates and spectra

Fig. 2

SNP heritability estimates (percentage of variance explained) for maternally phased DNMs in mothers (n = 7993, left), paternally phased DNMs (n = 7892, centre), and all phased DNMs across individuals (n = 15,885, right). Error bars represent two-tailed 95% confidence intervals for the heritability estimates. Estimates were calculated using the GREML-LDMS algorithm25 (Methods) for variants stratified by minor allele frequency (MAF) and linkage disequilibrium (LD). Light and deep blue bars represent variants with LD scores below and above the genome-wide LD median, respectively. Grey bars indicate estimates for all variants in each subset, without MAF or LD filtering.

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