Fig. 2: PHOTON captures the spatial transcriptome of granulosa cells (GCs) in the mouse ovary. | Nature Communications

Fig. 2: PHOTON captures the spatial transcriptome of granulosa cells (GCs) in the mouse ovary.

From: Subcellular level spatial transcriptomics with PHOTON

Fig. 2

A Morphologically guided targeting of GCs in the adult mouse ovarian tissue slices. A secondary follicle was visualized by the fluorescence of the photocaged cDNA molecules. Scale bar, 15 µm. B Expression levels of ovarian cell-type marker genes revealed by PHOTON. n = 2 independent replicates. Error bars represent a 95% confidence interval. C Comparison between the mouse GC transcriptome generated by the follicle isolation method and that generated by PHOTON. The schematic was created using BioRender. D Comparison between the mouse GC transcriptome generated by Slide-seqV2 and that generated by PHOTON.

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