Fig. 2: Tumour mutation burden, mutation spectra and recurrent copy number alterations. | Nature Communications

Fig. 2: Tumour mutation burden, mutation spectra and recurrent copy number alterations.

From: Wnt/β-catenin activation by mutually exclusive FBXW11 and CTNNB1 hotspot mutations drives salivary basal cell adenoma

Fig. 2

a Tumour mutation burden in salivary gland basal cell adenoma (BCA; n = 32) and basal cell adenocarcinoma (BCAC; n = 11). Boxplot annotations: centre line, median; box limits, upper (75th) and lower (25th) quartiles; whiskers, 1.5x interquartile range; points, tumour mutation burden of samples. b Penetrance plot of somatic copy number gains and losses in BCA (top; n = 32) and BCAC (lower; n = 11). c The single base substitution spectrum (top) and indel spectrum (lower) from PD56546c. Show are the number of mutations occurring in each of the 96 possible trinucleotide contexts for single base substitutions and specific repeat contexts for indels.

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