Fig. 5: Evolutionary origins and diversification of self-sustained Kai protein circadian oscillators.
From: Evolutionary origins of self-sustained Kai protein circadian oscillators in cyanobacteria

Divergence times were estimated on the basis of TimeTree53 analysis using 16S rRNA sequences. Filled circles and horizontal bars indicate estimated divergence times (1 Ga = 1 billion years) and confidence intervals, respectively (Supplementary Table 3). The approximate times of the emergence of the most recent common ancestor (MRCA) of cyanobacteria1,2,3,4,5,6, Great Oxidation Event (GOE)7, first and second Snowball Earth events (SEEs)8,9,10, the post-GOE period known as the “boring billion years” of ever-stable global conditions64, and the Neoproterozoic Oxygenation Event (NOE)11,12 are schematically shown for reference.