Fig. 2: Equilibrium dynamics of M and Mcoop models.
a Molecular traffic T(t) of M and Mcoop systems at the equilibrium. b Transition probability matrices (probability in %, with Δτ = 15 ns) of M and Mcoop systems. The diagram in the middle indicate the pathways defined by polymerisation (solid) and depolymerisation (dashed) of an assembly across the matrix. c Polymerisation and depolymerisation probability curves as a function of aggregate state (computed with Δτ = 15 ns). d Polymerisation/depolymerisation ratio as function of aggregate size (computed with Δτ = 15 ns). e Dynamic events detected by LENS descriptor43 for the M and Mcoop systems at the equilibrium. Four examples are reported herein (see Fig. S3 for the full analysis). Each event connects the conformations shown in the upper and lower circles: binding/unbinding of a free monomer (the purple monomer binds/unbinds from an existing fibre), polymerisation/depolymerisation of an existing fibre (binding/unbinding of green tip monomers), fibre bending/straightening (the blue monomers form/break a contact out of the fibre axis) and branching (orange monomer binds/unbinds with two blue monomers out the fibre axis). (right) Number of events detected for each type, the dashed line separates multimeric and monomeric events. The last columns (cream) indicate the total number of multimeric events.
