Fig. 5: Resilience of M and Mcoop systems upon chain-stopper insertion.
a Ppoly (solid) and Pdepoly (dashed) (with Δτ = 15 ns) as a function of the aggregate size, for M and Mcoop systems in equilibrium with different amounts of C. For large aggregates (size > 128) insufficient statistics provides inaccurate estimates of transition probabilities (the presence of such large aggregates is rare in the unperturbed systems, and they tend to disappear as the concentration of C increases). Poor statistics is indicated by shaded colours. b Relative probabilities of polymerisation (solid) and depolymerisation (dashed) of assemblies of different size-ranges, as a function of the C content (see “Methods” for details), for M and Mcoop systems. c Resilience (see text for the definition) of assemblies of different size-ranges, as a function of the C content, for M and Mcoop systems. d Normalised resilience of M (black circles) and Mcoop (red triangles) systems averaged over the strength of the perturbation (number of C), per each size range. The values are normalised so that the minimum is 0 and the maximum is 1, and quadratic fits (solid lines) are reported to highlight the different trends exhibited by the two systems. The blue dashed line indicates the average aggregate size in the unperturbed systems. e Equilibrium snapshots of unperturbed/perturbed M (left) and Mcoop (right) systems (500 monomers in equilibrium with 0 or 100 C). Different aggregates are coloured according to their size (see Supplementary Movie 1 for inter-assembly dynamics).
