Fig. 2: Higher separation of on-chip 3D secretion compared to 2D assay for BMAC donors. | Nature Communications

Fig. 2: Higher separation of on-chip 3D secretion compared to 2D assay for BMAC donors.

From: On-chip 3D potency assay for prediction of clinical outcomes for cell therapy candidates for osteoarthritis

Fig. 2

A Hierarchal clustering heatmap. Darker purple represents higher secretion value. B Discriminant analysis with biplot rays of normalized sample secretion (pg/pg) showing higher donor variability across on-chip 3D secretion not captured in 2D assay. Canonical score 1 and 2 account for 97.0% and 2.9% of the overall variance of the data. Analysis represents 24 secreted proteins of on-chip 3D and 2D samples, with and without simSF.

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