Fig. 3: Loss of endothelial and epithelial CXCR2 leads to reduced survival during K. pneumoniae-induced pneumonia. | Nature Communications

Fig. 3: Loss of endothelial and epithelial CXCR2 leads to reduced survival during K. pneumoniae-induced pneumonia.

From: Alveolar epithelial and vascular CXCR2 mediates transcytosis of CXCL1 in inflamed lungs

Fig. 3

CXCR2 KO mice (red=CXCR2−/−, green=CXCR2fl/flCdh5Cre+, blue=CXCR2fl/flShhCre+) and appropriate WT/Cre- control (gray) mice were intratracheally administered with a lethal CFU dose of viable K. pneumoniae. A–C Survival was analyzed 24 h. Data are mean ± SD, n = 5–8 biologically independent mice pre group, age 8–16 weeks, equal gender distribution, Kaplan-Meier analysis, *p < 0.05.

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