Fig. 6: Synthesis and characterization of PEGylated Dye. | Nature Communications

Fig. 6: Synthesis and characterization of PEGylated Dye.

From: Near-infrared II cyanine fluorophores with large stokes shift engineered by regulating respective absorption and emission

Fig. 6

A Conjugatable design of VIPI-2-COOH. The pharmacokinetics of (B) VIPI-2 and (C) VIPI-2-mPEG2000 in mice after tail vein injection (VIPI-2: 500 μM, 200 μL in saline containing 1% DMSO; VIPI-2-mPEG2000: 500 μM, 200 μL in saline) determined by NIR-II imaging. DThe fractions of urine excretion of VIPI-2 and VIPI-2-mPEG2000 within 8 h after intravenous injection. Data are presented as mean ± standard deviation; n = 3 mice for panels B, C and D.

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