Fig. 1: CONSORT diagram of volunteer recruitment. | Nature Communications

Fig. 1: CONSORT diagram of volunteer recruitment.

From: Early mucosal responses following a randomised controlled human inhaled infection with attenuated Mycobacterium bovis BCG

Fig. 1

The first volunteers were screened on 19th March 2019 and enrolment commenced on 29th April 2019. The final volunteer was enrolled on 12th February 2020, and the last volunteer visit was 30th July 2020. Volunteers were randomised to receive either 1 × 107 CFU aerosol BCG Danish (Group A) or aerosol saline (Group B) with a bronchoscopy at either Day 2 (D2; Group 1) or Day 7 (D7; Group 2) following inhalation. Volunteers were blinded to intervention. Reasons for exclusion during screening included blood dyscrasias, respiratory disease or poor baseline lung function, IGRA positivity.

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