Fig. 4: Recombinant HKU5 RBD and spike bind to Pipistrellus abramus ACE2.
From: ACE2 from Pipistrellus abramus bats is a receptor for HKU5 coronaviruses
Recombinant RBD or spike proteins were immobilized on ELISA plates and incubated with increasing amounts of the indicated receptor-Fc fusion protein or with a BSA-only control. Each data point is the mean of four measurements with bars indicating standard deviations. Binding to Pipstrellus abramus ACE2 is indicated in orange lines with circles, human ACE2 is indicated in red lines with squares, and human DPP4 is shown in blue with triangles.
