Fig. 5: Clade consensus RBDs mimic clade-specific entry.
From: ACE2 from Pipistrellus abramus bats is a receptor for HKU5 coronaviruses
a Consensus sequences were generated for clades 1, 2, and 4. b 293 T cells transfected with indicated receptors were infected with chimeric spikes bearing clade consensus RBDs, in quadruplicate as technical replicates. The mean is shown as a bar and lines indicate standard deviation. c Schematic overview of sarbecovirus and merbecovirus RBD clades, indel patterns and receptor use.
