Fig. 6: Direct synthesis of structurally diverse chiral organogermanium from simple germanium tetrachloride.
From: Synthesis of chiral germanium center enabled by poly-deborylative alkylation and desymmetrization
a Germanium tetrachloride could be selectively functionalized using deborylative alkylation reaction illustrated in the Fig. 2. Merging those transformations with copper catalyzed the desymmetrization provided an universal approaches to access the chiral germanium center with great structure diversity. b Post-functionalization of the chiral germanane 80. For detailed reaction conditions, see the synthetic application section in the supporting information.
