Fig. 2: Accuracy evaluation of DeconmiR and comparison with other methods.

A Deconvolution results of simulated rare components with varying degree, the changes of RMSE and R² values agree with different rare component proportions (n = 100 replicates at each proportion level). The boxes are bounded by the 25 and 75 percentiles and the center represents the median. The whiskers extend from each edge of the box to indicate the 1.5× interquartile range (IQR). B Averaged RMSE and R² value for deconvolution results of simulated rare components with varying degree. C DeconmiR predicts relative cell fractions of 14 samples from adult human whole blood with flow cytometry fractions, the corresponding RMSE and R² values for the comparison are presented. P-value is derived from the Pearson correlation test. D Comparing DeconmiR with other deconvolution methods, barplots of RMSE and R² values for the estimated cellular proportions for the four different algorithms applied to the reconstructed mixture samples. E Average RMSE and R² values for different algorithms across different cell types. Source data are provided as a Source Data file.