Table 2 Patient serum and CSF autoantibody NMDAR internalization activity equivalent to activity of 502 Ab and minimum effective reversal concentration of ART5803
From: Monoclonal humanized monovalent antibody blocking therapy for anti-NMDA receptor encephalitis
Patient ID | Serum | CSF | ||
|---|---|---|---|---|
Equivalent to internalization activity of 502 Ab [μg/mL] | Minimum effective conc. of ART5803 [μg/mL] | Equivalent to internalization activity of 502 Ab [μg/mL] | Minimum effective conc. of ART5803 [μg/mL] | |
#1 | 5.5 | 10 | 1.4 | 2.5 (74%) |
#2 | 1.7 | 10 | 0.56 | 1.3 |
#3 | 1.5 | 3.0 | 0.94 | 0.63 |
#4 | 2.0 | 3.0 (81%) | ND | - |
#5 | 1.4 | 10 | ND | - |
#6 | 2.6 | 3.3 | ND | - |
#7 | 1.0 | 3.0 | ND | - |
