Fig. 5: Application of the (hetero)arenes C(sp²)−H borylation and scope extension to borylation of aryl bromides and anionic polymerization.

a Borylation of methoxylmethyl (MOM)-protected (R)-BINOL and a comparison to the previous strategy. b Cascade C(sp²)−H borylation/Suzuki-Miyaura cross-coupling for the structural diversification of drug-relevant substrates. c Cascade borylation of aryl bromides/Suzuki-Miyaura cross-coupling for the synthesis of biaryls. d Benzylic boronate/KO^tBu combination-initiated polymerization of 4-chlorostyrene under different conditions. ^aWithout further purification by column chromatography on silica gel. ^bS47 (0.2 mmol), 1d (1.1 equiv) and KO^tBu (1.5 equiv) in 1.0 mL of THF at 40 °C, 5 h, under Ar. ^cS48 (0.1 mmol), 1d (1.5 equiv) and KO^tBu (1.5 equiv) in 1.0 mL of THF at 60 °C, 5 h, under Ar. ^dWith KO^tBu. ^eWith NaO^tBu.