Table 2 Demographics and treatment parameters of primary PD cohort

From: Boundary complexity of cortical and subcortical areas predicts deep brain stimulation outcomes in Parkinson’s disease

Clinical Feature

Total

∆LEDD ≤ 0

∆LEDD > 0

Subjects (n)

231

60

171

Male (n)

155

40

115

Female (n)

76

20

56

Mean Age (years)

65 ± 9

66 ± 7

64 ± 10

STN Target (n)

96

6

90

GPi Target (n)

135

54

81

Unilateral (n)

44

15

29

Bilateral (n)

187

45

142

Mean Motor Improvement (%)a

53 ± 16

54 ± 15

52 ± 17

Mean ∆LEDD (%)b

23 ± 36

−22 ± 22

39 ± 25

  1. LEDD levodopa equivalent daily dose, STN subthalamic nucleus, GPi Globus Pallidus Interna
  2. aBased on preoperative MDS-UPDRS III exam on- and off-medications.
  3. bBased on patients’ dosage regimen before versus after approx. 6 months of DBS.